suPARnostic® - The Risk Status Marker
A novel biomarker for critical care situations, e.g.sepsis, acting as a master alarm for developing critical conditions. A simple test to help in triage, treatment and monitoring.
It has been published that no genetic polymorphisms exist causing humans to naturally express high levels of suPAR, indicating that elevated concentrations of suPAR can be exclusively attributed to immune activation or immune response to a specific challenge.
Several thousand individuals were investigated in a population study to obtain the “healthy” baseline, which varies slightly depending on gender and age.
For more information about the suPARnostic® table, please look under
Products - Result Interpretation
With age the healthy suPAR baseline rises and women have a slightly higher baseline than men – a fact that so far has not been explained at the scientific level.
The definition of the yellow(“OBSERVATION”) and red (“CRITICAL”) range is based on all patients screened so far and their respective history and outcome. As work with suPARnostic® progresses and data are added to the statistical pool, the respective numbers and ranges for corresponding clinical read-out will become more and more precise.
Read more in our suPARnostic® Application notes:
- No. 1A: suPAR Background suPAR note 1A Background (967.24 KB)
- No. 1B: suPAR Stability and usage suPAR note 1B Stability and usage (779.90 KB)
- No. 4: Severity Biomarker in SIRS/Sepsis Patients suPAR note 4 Sepsis (693.92 KB)