ICU - Patient Monitoring
suPARnostic® is a vital tool in critical care situations that involve conditions which need to be monitored closely – a sepsis or potential sepsis case for example. Running a suPARnostic® test on a patient provides clinicians with information that aids in treatment and monitoring decisions.
For example, we recently found that suPARnostic® levels can predict both short- and long-term mortality in adult SIRS patients admitted to an emergency department. Our results demonstrate that suPARnostic® used either independently (AUC =0.80) or in combination with age (AUC=0.92) is a strong predictor of mortality in SIRS patients suspected of community-acquired infections. It is believed that mortality rates and recovery can be vastly improved by early accurate diagnosis and treatment of septic patients.
In addition, suPARnostic®'s ability to accurately track a patient’s disease progression will serve to reduce repeated testing and treatment costs. Our studies clearly indicate the benefit of evaluating a patient’s suPARnostic® level all the way from diagnosis to hospital discharge.
As per the suPARnostic value spectrum (for more informationabout the spectrum, please look under ), developed and refined over years of intensive research, the following guidelines can be applied for the use of suPARnostic as a monitoring tool:
A patient in the "CRITICAL" area as per the above suPARnostic® spectrum has a high mortality risk; if the suPARnostic® level does not decrease or continues to increase in spite of treatment and while blood parameters commonly used in acute care may normalize, treatment should be modified and/or other potential pathologies should be investigated and treatedas fast as possible.
A patient with a suPARnostic® level in the "OBSERVATION" range needs to be monitored closely for increasing or decreasing suPARnostic® level: Decreasing levels indicate improvement and treatment response, increasing levels indicate worsening condition and insufficient treatment response; a complication could develop and perhaps be prevented.
Patients whose suPARnostic® values decrease to the "HEALTHY" range and stay there and whose other standard blood parameters are in the normal range can be discharged from acute care.
See the movie of Dr Marek Paradowski´s speech from the 2´nd International suPAR Symposium here:
Marek Paradowski – "Case stories from ICU in Poland"
We suggest to open the movie in Quick Time Player to avoid unnecessary loading time.
Please find link to download Quick Time Player here